Category Archives: News Review

New Theory on the Action of Antidepressants News Round-Up February 2014 1st Edition

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Scientific American elaborates on a recent theory about the action of antidepressants. The theory states that antidepressants enhance the processing of positive emotions while dampening the processing of negative emotions. Furthermore the theory states that this action occurs quickly. A cumulative effect results in the changes seen in the medium term. This theory should generate an interesting debate.

via @vaughanbell, the Dana Foundation has a piece on memory research in the last few decades.

Humans express four basic emotions according to this study.

Chris Chambers looks at the changes happening in Psychology research and how this might impact on other branches of the life sciences.

International Psychoanalysis have an interesting piece contrasting the two main proponents of the philsophy of science – Thomas Kuhn and Karl Popper.

Appendix

News Round-Up 2008-2011

News Round-Up 2012

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest: For potential conflicts of interest please see the About section.

Research Productivity in Mental Health Mapped in NHS News Roundup January 2014 4th Edition

Dr Alex Mitchell and medical student John Gill have published a paper on the research productivity in NHS mental health services. The paper is published in the open-access journal ‘The Psychiatric Bulletin’ TPB *.

This open-access TPB paper looks at the effects of using national and European guidelines on neuroimaging in memory services on the practice in one service.

Can librarians be integrated into mental health services? This open-access TPB paper summarises a pilot study into the integration of a clinical librarian into 4 mental health teams. Benefits identified included the rapid assembly of evidence to answer specific clinical questions.

This open-access TPB paper on an audit of the management of Wernicke’s Encepalopathy also looks at the evidence base.

Researchers in two studies have mapped the neuroanatomical and temporal progression of the spread of the misfolded protein TDP-43 through the brain in Dementia In Alzheimer’s Disease and Frontotemporal Dementia.

Appendix

News Round-Up 2008-2011

News Round-Up 2012

News Round-Up 2013

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest*: For potential conflicts of interest please see the About section.

‘The Psychiatrist’ Becomes ‘The Psychiatric Bulletin and Goes Open Access News Round-Up January 2014 3rd Edition

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One of the main UK Psychiatry journals, ‘The Psychiatrist’ has reverted back to the original name of ‘The Psychiatric Bulletin’ and now features open-access articles*. Here are the 5 current open-access articles available online

  • A look at Community Treatment Orders (CTO’s) in an editorial which recognises the role of public debate.
  • An editorial looking at the evidence on CTO’s from the OCTET (Oxford Community Treatment Order Evaluation Trial).
  • A special article looking at the significance of the OCTET from another perspective
  • A study looking at the effects of additional conditions on CTO’s.
  • A study looking at the effects of CTO’s on management in an assertive outreach team in London.

All of the above articles feature a Creative Commons 3.0 License which means they can be reused within the conditions of the license.

Elsewhere in the news.

An interesting PLOS One study looked at coverage of clinical trials in the media. The authors concluded that Randomised Controlled Trials were less likely to be reported than Observational studies. The latter would feature lower on the hierarchy of evidence than RCT’s. In essence the study implies that the more methodologically robust studies are less likely to be reported on.

A reduction in right Parietal Cortex grey matter volume may be linked to the subtle memory impairment that can be seen in Parkinson’s Disease according to this study.

Appendix

News Round-Up 2008-2011

News Round-Up 2012

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest*: For potential conflicts of interest please see the About section.

Framingham Heart Study Data Suggests Link Between Cardiovascular Health and Dementia Risk News Round-Up January 2014 3rd Edition

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Two features of Dementia in Alzheimer’s Disease are basal forebrain atrophy and a build up of Amyloid plaque. Neuropathology studies have found a link between the two. Now a recent study (n=225) used a combination of PET and structural MRI to investigate this relationship. The results in this study again supported this relationship.

Researchers in this study (n=138) used biomarker data from the Alzheimer’s Disease Neuroimaging Initiative to investigate amnestic Mild Cognitive Impairment (MCI). The researchers were able to stratify people with amnestic MCI.

Biomarkers for Dementia in Alzheimer’s Disease (DAT) were investigated in this study. Researchers followed up 340 people over 10 years. They found medial Temporal lobe atrophy was associated with incipient DAT up to 5 years in advance. They also found that Tempoparietal Cortex involvement was associated with the preclinical phase of DAT.

The Framingham Heart study is a long term study looking at cardiovascular health. A recent analysis of the data was published. The researchers found 777 cases of incipient Dementia in 7901 people. Researchers found that the lifetime risk at age 45 was

1:5 for women

1:10 for men

The researchers also found that cardiovascular mortality in adult men decreased with age. Essentially these findings suggest that men surviving into older adulthood in the study have better cardiovascular health than men at a younger age in the study. As cardiovascular health is linked to Dementia risk this may explain the difference in findings in men and women.

New Scientist have an interesting article on musical hallucinations.

Evolution/Evolutionary Psychiatry/Culture

John Hawks has an interesting article on self-medication in H.Neanderthalensis.

Appendix

News Round-Up 2008-2011

News Round-Up 2012

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest: For potential conflicts of interest please see the About section.

SHY Theory on Sleep Elaborated News Round-Up January 2014 2nd Edition

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Microglia may play a role in Depression according to this study, however more data is needed in humans to provide a stronger evidence base for this hypothesis.

There is an interesting editorial on the broadening of topics in the Schizophrenia Bulletin to cover related conditions with psychosis.

BMC Medicine celebrated 10 years of open-access medical publishing including the CONSORT statement on standards for reporting trials.

Researchers have utilised data from the World Health Organisation and published studies to create a data repository. The repository can be used to compare incidence rates globally.

Traumatic brain injury led to Amyloid build up in some cases in this study.

Miscellaneous

New Scientist has an interesting piece on the phenomenon of lifelogging whereby we use technology to record many aspects of our life. Lifelogging may lead to an enhancement of our life including health and this is discussed.

Neuroscience

Researchers have found evidence of a protein that may be involved in pathways leading to obesity. The protein alpha-2/delta-1 was found to influence the function of Brain Derived Neurotrophic Factor. As well as a role in exercise associated synaptic growth, BDNF is linked to appetite suppression.

In an elaboration of the hypothesis the authors of the SHY hypothesis suggest that we sleep because we learn. Sleep enables us to reset synapses in the brain which in turn promotes new learning on waking and reduces energy demands in the brain.

Evolutionary Psychiatry/Evolution/Culture

Researchers at Oxford have looked at the dietary habits of Baboons to infer the likely diet of Paranthropus Bosei, one of our distant relatives that lived between 1.4 and 2.4 million years ago. P.Bosei had large teeth which would have been well suited to chewing and the researchers hypothesise that they would have fed on grass bulbs (tiger nuts) that are seen in modern diets.

Appendix

News Round-Up 2008-2011

News Round-Up 2012

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest: For potential conflicts of interest please see the About section.

Looking Back at 2013 News Round-Up January 2014 1st Edition

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A number of organisations and publishers have been looking back at 2013.

Alzforum have an overview of the main research developments in 2013 in Dementia including Dementia in  Alzheimer’s Disease.

Miscellaneous

The BBC have a very good overview of science developments in 2013.

Wikipedia have a good overview of science developments in 2013.

Scientific American have an overview of the 10 science stories of 2013.

Science Mag have created a video overview of important science findings from 2013.

The British Library has made available more than one million public domain images on Flickr encouraging people to reuse the images in creative ways.

NHS Hack Day is taking place in Cardiff on 25th and 26th January 2014.

Neuroscience

There is an interesting write-up of a recent theory about memory formation here. The theory states that the location of memory storage is dependent on the frequency of recall. The theory also accounts for how memories change.

There is a write-up here of research revealing a phenomenon known as ‘mindless accumulation’. The phenomenon describes the tendency of people to work to overachieve their targetted goals so that they have material gains beyond the stated immediate need. The experimental environment was artificial in that listening to white noise was rewarded with chocolates. These findings may be helpful in better understanding the factors influencing work-life balance.

The Great Brain Experiment took place last year but there are some additional games that readers can upload onto their mobile devices. The researchers have turned their research into games making the research experience a lot more fun!

Appendix

News Round-Up 2008-2011

News Round-Up 2012

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest: For potential conflicts of interest please see the About section.

Genome Data from NIMH Alzheimer’s Disease Sequencing Project Released News Round-Up December 2013 4th Edition

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The National Institute of Health has released the genome data from their Alzheimer’s Disease sequencing project. The project includes 410 people within 89 families.

Virginia Hughes looks at a study comparing aging in 46 species including humans with some interesting results.

Neuroscience

The replication of 10 out of 13 effects in psychological studies has been widely reported. At a superficial level it seems promising that a large proportion of the effects can be replicated. However in the above link Tal Yarkoni provides a more detailed assessment with reference to the blogosphere.

What does compassion sound like? This study has an answer.

Evolutionary Psychiatry/Evolution/Culture

New Scientist has an interesting subscription article about how Kalahari hunters were recruited to interpret footprints from the Ice Age in a cave in France.

One of the mutations leading to Diabetes in humans appears to have been inherited from Neanderthals according to this study.

Appendix

News Round-Up 2008-2011

News Round-Up 2012

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog. Conflicts of Interest: For potential conflicts of interest please see the About section.