Review: Cognitive Impairment in MS: Evidence-based analysis


The article reviewed here is ‘Cognitive Impairment in Multiple Sclerosis: Evidence-based Analysis and Recommendations’ by Jeffrey Rogers and Peter Panegyres. While the review is highly structured, there is no methodology outlined, which might be useful for instance for those wanting to update the review. In the introduction the authors outline some of the associations of cognitive dysfunction in Multiple Sclerosis (MS) including those in the area of employment and rehabilitation. The authors then look at the neuropsychological profile of MS covering processing speed, memory retrieval and attention amongst others. Neuroanatomical considerations are addressed briefly before the authors turn to factors which influence cognitive dysfunction. This was a useful section examining factors such as disease subtype and duration. They then look at screening tools for cognitive dysfunction in MS drawing attention to the performances of the Paced Auditory Serial Addition Task and the Clock Drawing Test. Although there are a number of reviews of cognitive dysfunction in MS and this one is now 2 years old, the subject is sufficiently broad for this to be useful and I found the section on screening to be particularly informative.


Jeffrey M Rogers and Peter K Panegyres. Cognitive Impairment in Multiple Sclerosis: Evidence-based analysis and recommendations. Journal of Clinical Neuroscience. 14. 2007. 919-927.


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