News Round-Up: June 2010

As the World Cup action is underway this week, I’ve added a medical(ish) section at the end on football which links to a number of papers in this area. There is a particularly interesting paper on watching stressful matches which emphasises some of the potential risks and the authors comment on the implications. There are also articles on dehydrated referees, headaches in footballers (literal not metaphorical) and a potential role of coaches as mental health advocates. In the main news there has been a recent paper on the genetics of autism which has been widely reported (3) and the mechanism underlying the action of the Presenilin 1 gene which leads to pre-senile Alzheimer’s Disease has been identified (1). Personal genomics is a fast emerging area with an ambitious plan to sequence 100,000 genomes (17). However there was a recent alleged mix-up in which the information on several people’s genomes were sent to the wrong recipients (13). Meanwhile the Frontier Psychiatrist reports on a recent conference in which recruitment into psychiatry was discussed.

  1. Mechanism of presenilin gene action in pre-senile Alzheimer’s Diseaes cracked http://bit.ly/9yVRwb.
  2. The Coalition against Major Diseases is setting up a database to share research on neurodegenerative diseases.
  3. Neat article on the genetics of autism http://bit.ly/bZIIFv.
  4. Study estimates more deaths at weekends in hospitals – suggests reason http://bit.ly/bH34M5.
  5. Cognitive decline in people with diabetes more rapid than control group in longitudinal study reported here.
  6. Free paper on insular cortex response to SSRI’s in healthy volunteers http://bit.ly/cb8wqo.
  7. Meta-analysis of monotherapy in bipolar disorder http://bit.ly/93k1vi.
  8. Free paper – small study showing association between reduced glutamic acid decarboxylase (GAD) in PFC and MDD http://bit.ly/c9oQii
  9. Good response to Lithium in Bipolar Disorder is associated with normal BDNF levels http://bit.ly/d6Yb0t
  10. PET study finds quetiapine binds preferentially at extrastriatal D2/3R’s similar to Clozapine http://bit.ly/aC7nZL
  11. BDNF Val66Met SNP rs6265 significantly associated with verbal memory in Swiss study n=333 http://bit.ly/aOMS7P
  12. Evidence suggesting that Ghrelin secreted in brain regulates cholesterol levels http://bit.ly/d0sHJp.
  13. Personal genomics data mix-up.
  14. Scientific American article describing evidence supporting the scanning hypothesis of REM sleep.
  15. A discussion of advances in computational visual neuroscience with a video interview.
  16. Brief article on integrating genomics into doctors visits.
  17. The plan to sequence 100,000 genomes.
  18. At least 2000 missing gene sequences in the reference human genome.
  19. Jumping genes vary between individuals http://bit.ly/9aAask.
  20. Cardio Trace Monitors used to assess arterial stiffness – might have widespread applications.

Resources –  Review Articles

  1. Free r/v article on the science of mediation http://bit.ly/cl5hAn.
  2. Subscription r/v article on ‘core’ social cognitive neuroscience processes http://bit.ly/aHv9K2.
  3. Subscription r/v article on cross-cultural organisational behaviour http://bit.ly/ciXB9Q.
  4. Subscription r/v article on cognition in organisations http://bit.ly/93gJfg.
  5. R/V article on the evolution of empathy http://bit.ly/9EaGvB.
  6. Subscription r/v article on grounded cognition http://bit.ly/dc4g6W.
  7. Subscription r/v article – the science of personnel selection http://bit.ly/a0yi6g.
  8. Subscription r/v article on the concept of short-term memory http://bit.ly/9ctM7K.
  9. Subscription r/v article on why the laws of memory haven’t stood the test of time http://bit.ly/97D5Tk.
  10. Free article on neuropsychological assessment of dementia http://bit.ly/b9k5nm.
  11. Free r/v article on children’s construction of concepts http://bit.ly/bnNcQQ.
  12. Subscription r/v article on theories of leadership http://bit.ly/a3gmHX.
  13. Subscription r/v article on relation between speech, reading and language disorders http://bit.ly/bzniwp.
  14. Free r/v article on emotions http://bit.ly/brgnun.
  15. Subscription r/v on comparative social cognition http://bit.ly/b5kxGJ.
  16. Subscription r/v article on evolution of intention and actions http://bit.ly/cEJ9N1.
  17. Subscription r/v article on research into close relationships http://bit.ly/dlMFry.
  18. Subscription r/v article on creativity http://bit.ly/adT933.
  19. R/V article on the empirical investigation of negotiation http://bit.ly/d8OkIR.
  20. Subscription r/v article on emotional and social aging http://bit.ly/dm2oFD.
  21. Subscription r/v article on cognitive neural prosthetics http://bit.ly/dujyl7.
  22. Subscription r/v article – concepts needed for investigating love http://bit.ly/cwxDEL.
  23. Subscription r/v article on possible role of hippocampus in imagination and prediction! http://bit.ly/ch7ajp.
  24. R/V article – ‘multidimensional’ odours http://bit.ly/cw3vOj.
  25. 2007 r/v article of copper and iron disorders of the brain http://bit.ly/bmtdUa.
  26. R/V article on ventral tegmental area and reward http://bit.ly/956PrK.
  27. R/V article of orbitofrontal cortex and decision-making.
  28. Free 2007 article on medial temporal lobe and recognition memory http://bit.ly/biEBzX.
  29. Free 2007 r/v article on glia in blood-brain barrier function http://bit.ly/btm22G.
  30. 2008 r/v article on cerebellum function http://bit.ly/bqzJBp.
  31. 2008 r/v article on place and grid cells http://bit.ly/9smB2A.
  32. Free r/v article on passive v active immunity tx for neurodegenerative disorders http://bit.ly/9loItY.
  33. Free r/v – mechanisms of face perception http://bit.ly/af0ipd.
  34. Free r/v article on primate auditory cortex http://bit.ly/aoK937.
  35. R/V of numbers in the brain – evidence that numbers represented in animals http://bit.ly/9EKbu9.
  36. R/V of diffuse tensor imaging and neuroanatomy http://bit.ly/9L8f52.
  37. R/V of serotonin and affect – asymmetry of reward & punishment http://bit.ly/ddM6sA.
  38. Free r/v article by Woolf on neuropathic pain http://bit.ly/d295ET.
  39. Free r/v article – monoamines and prefrontal cortex http://bit.ly/bp6K24.
  40. R/V cerebellum and non-motor function http://bit.ly/cWzN9s.
  41. Free article – advances in microscopy for neuroscience http://bit.ly/8X64Jb.
  42. Apparently subplate neurons may be particularly susceptible to injury in foetal development http://bit.ly/a6NPAN.
  43. R/V of subplate in neural development http://bit.ly/a6NPAN.
  44. R/V of emotion in amygdala and pfc http://bit.ly/cUu6LP.
  45. R/V of prefrontal cortex in moral judgement http://bit.ly/a3baUX.
  46. R/V of connectn between nervous & vascular systems http://bit.ly/9mQGEj.
  47. R/V molecular pathways in frontotemporal lobar degeneration http://bit.ly/9Tuh88.
  48. Article – why do we still have maternally inherited mitochondrial DNA? http://bit.ly/ceAkpG.
  49. Free article – r/v of chromatin structure and function http://bit.ly/9OEMMU.
  50. Free article – rv of p kinase degradation by ubiquitination http://bit.ly/ap45yf.
  51. Free article – super-resolution fluorescence microscopy http://bit.ly/dmR7dk.
  52. Cholesterol turnover in the brain – free article http://bit.ly/9NA845.
  53. R/V of zinc fingers and genome manipulation http://bit.ly/a8gLzE.
  54. Unnatural amino acids http://bit.ly/bi3CIx.
  55. R/V of Mitochondrial DNA mutation and aging http://bit.ly/94Sutw.
  56. Review of screening of genomes with RNA interference http://bit.ly/aHJoEo.

Psychiatry 2.0

Football-Related Articles

Call for Authors: If you are interested in writing an article or series of articles for this blog please write to the e-mail address below. Copyright can be retained. Index: An index of the site can be found here. The page contains links to all of the articles in the blog in chronological order. Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

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