News Round-Up: June 2010 3rd Edition

In the news round-up this week, there has been a lot of media coverage around the installation of robots in a hospital in Scotland which will take on a number of roles (2). There are also studies looking at the associations of excess alpha synuclein (1), the limitations of classification software for discriminating mild cognitive impairment from Alzheimer’s Disease (7) as well as confirmation of the associations between the genes CR1, CLU and PICALM and Alzheimer’s Disease (8). There are interesting studies which have the potential to expand the concept of Mild Cognitive Impairment where difficulties with using technology (14) as well as semantic impairment (18) were found.

  1. Coverage of studies suggesting extra alpha-synuclein is pathological
  2. Robots used in hospital in Scotland & appears to be from this company from acronym
  3. Subs article – Korean study on risk neuropsychiatric syndromes in AD
  4. Subscription article – preliminary evidence of mitochondrial haplotype assoc with AD
  5. Subscription article – MRI surface mapping study suggests right caudate atrophy in AD
  6. Subscription article – small study showing dissociation of cerebral atrophy and regional cerebral perfusion in MCI & AD
  7. Subscription article – classification algorithms useful for AD v Controls but not AD v MCI from ADNI
  8. Subscription article – large cohort study confirms CR1, CLU, PICALM association with Alzheimer’s Disease
  9. Free paper on Portuguese cognitive impairment study – rural v urban prevalence
  10. Important free article on NIH consensus on preventing cognitive decline
  11. Subscription article – Evidence of slowed retinal response association with early AD
  12. subs article – risk of cerebral microbleeds (mbs) in memory clinic assoc with baseline mbs + APOE epsilon genotype
  13. subs article – small study showing evidence of impaired dual task performance in VaD
  14. Subscription article – ability to manage technology impaired in mild cognitive impairment
  15. Subscription article – Evidence of faster rate of cog decline in Alzheimer’s Disease when new vascular lesions
  16. Subscription article – prospective 24 week trial on Rivastigmine in Parkinson’s Disease with dementia
  17. Subscription article – pathological evidence of Lewy Body disease without clinical features
  18. Subscription paper – semantic impairment in mild cognitive impairment
  19. Subscription article – vocabulary and lobar atrophy interact to predict learning in MS
  20. Analysis of ADL’s in 6 x Donepezil studies which should be interpreted in terms of the excluded studies
  21. HMG-CoA reductase inhibitor use in early v late old age and AD
  22. Subscription article – preliminary study investigating use of default mode network in assessment of AD


  1. Subscription article – Review of epidemiology of dementia in Parkinson’s Disease
  2. Subscription article – Review of interactions between NIDDM, depression, AD and PD
  3. Subscription article – review discussing lipid metabolism and Alzheimer’s Disease

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