Brodmann Area 6 corresponds to both the Premotor Cortex (PMC) and the Supplementary Motor Area (SMA) (which is distinct from the preSMA).
In this paper, the author suggests that the mirror neurons which have been found in the PMC may play a role in learning to play music as cells in this area are active both during motor activities and sensory stimulation. In this meta-analysis the authors suggest that the mirror system and the mentalising systems are complementary to each other and they refer to over 200 fMRI studies that support the role of the PMC and the Anterior Intraparietal Sulcus in producing the mirror system. The role of the PMC and the mirror neuron system in imitation is discussed in this meta-analysis. The possible role of mirror neurons in the PMC in recovery from aphasia in the context of research using Transcranial Magnetic Stimulation is discussed in this paper. The authors of this paper discuss research supporting a role of the Ventral Premotor Cortex in both music and language. The clinical implications of the mirror neuron system are discussed in a paper which is freely available here. Damage to the Premotor Cortex including the Frontal Eye Fields following a Right Middle Cerebral artery stroke was associated with an impairment of egocentric spatial representation in one case. The PMC is included in a model of embodied semantics in this paper.
In this paper the SMA is included amongst a number of brain regions involved in estimating duration (i.e time)(and in this paper as well as this freely available paper). The SMA is one of the targets for improving motor performance in Parkinson’s Disease. The possible functions of the SMA are reviewed in this paper. The large number of areas that connect with the SMA are commented on in this paper and a role in psychosis is postulated. The role of the SMA in learned actions is discussed in this paper. The role of the motor Thalamus which amongst other structures receives projections from the SMA is discussed in relation to neurosurgery in this paper. The relationship of akinesia to hypoactivation of the SMA is discussed in this paper. A case of gait apraxia associated with a bilateral SMA lesion is discussed in this freely available paper. The possible role of the SMA in language and more specifically the consonant-vowel frame is discussed in this paper. The activation of the SMA during musical imagery is discussed in this paper. The SMA is one of a number of areas active during word reading in discussed in this freely available paper. In another freely available paper the authors discuss the role of the SMA in verbal working memory. The role of the SMA in skilled performance is discussed in this freely available paper.
Thus the SMA in particular is a well connected part of the brain. Whilst both the SMA and PMC form part of Brodmann Area 6 they are understood to have very different functions. The mirror neurons are characteristic of the PMC and the mirror neuron system a very well developed body of research literature. The role of the SMA has been explored in relation to a number of functions from skilled performance through to reading, psychosis and akinesia.
Appendix – Articles Reviewed in relation to Brodmann Areas or other Structures
Brodmann Area 1 – Somatosensory Cortex
Brodmann Area 2 – The Primary Motor Cortex
Brodmann Area 6 (Agranular Frontal Area 6)
Brodmann Areas 5 and 7 (Somatosensory Association Cortex)
Brodmann Areas 13 and 14 (Insular Cortex)
Brodmann Area 15 (Anterior Temporal Lobe – Controversial Area in Humans)
Brodmann Area 25 – Anterior Cingulate Cortex
Brodmann Area 27 (Piriform Cortex)
Brodmann Area 28 (Entorhinal Cortex)
Brodmann Areas 45, 46, 47 (Inferior Frontal Gyrus)
Medial Temporal Lobe
Miscellaneous Subcortical Structures
Generic Articles Relating to Localisation
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