In an American study looking at older adults admitted to hospital and followed up 3 months after discharge the researchers found that at follow-up 81% of those that were depressed had been depressed on admission to hospital. The researchers interpreted this to mean that most of the cases of depression at follow-up represented persistent depression rather than new onset of depression during the course of the admission.
In a study of 56 people with DSM-IV diagnoses of Major Depressive Disorder with psychotic features, 41% had revised diagnosis within 2 years including Bipolar Disorder.
At the Alzheimer’s Research Forum there is an interesting write-up of a small research study which combined functional and structural Magnetic Resonance Imaging (MRI) findings. The study provided evidence of increased activity in the hippocampus being correlated with a reduction in cortical volume in a network which has been associated with changes in Alzheimer’s Disease. It will be interesting to see the results of further replication studies.
In a 10-year prospective cohort study, 163 people without cognitive impairment were assessed on their dietary habits at baseline and grey matter volume was assessed 10-years later (using MRI) together with neuropsychological assessments. The researchers found evidence of a significant association between consumption of boiled or baked fish and improved working memory as well as preservation of grey matter volume of 10 years later. The researchers were careful to control for a number of well-known confounders.
An index of the site can be found here. The page contains links to all of the articles in the blog in chronological order. Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail firstname.lastname@example.org. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.