David Austin’s grandmother developed Alzheimer’s Disease and later passed away. He has now set out to help people with Alzheimer’s Disease by building a large computer to run software which will help research into Alzheimer’s Disease. He is raising money at this website and when the computer is built will run a software program from the Rosetta@home project which run 3-dimensional protein folding simulations to better understand the proteins involved in different illnesses. Although the project is looking at a number of illness related proteins, part of this project is looking at proteins which form Amyloids. Amyloids are misfolded proteins and according to the Amyloid hypothesis, Amyloid formation is part of the chain of events leading to Alzheimer’s Disease. This is a great example of Science 4.0 in action.
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