Potential Benefits of Increased Mental Activity and #50 Online Tools for Science Education December 2012 1st Edition

Treatment of Attention Deficit and Hyperactivity Disorder was associated with a reduction in crime rates in this study (see @ProfLAppleby).

Time covers the treatment of an excessive sleep disorder using Flumazenil in Kleine-Levin disorder here.

There is a write-up here of a study which found evidence of a benefit for increased mental activity (e.g reading). The study used Magnetic Resonance Imaging to look at a marker for cell damage and found this to be reduced as activities such as reading increased although this was assessed using retrospective recall. It will be interesting to see the results of further replication studies.

Virtual reality has been used to teach social skills to people with Autism in one study.

One systematic reviewed looked at the management of dysphagia in Dementia and finding the prevalence ranged from 13 to 57% in the examined studies.

The dual syndrome hypothesis of Parkinson’s Disease is covered in this post which looks at the roles of Dopamine and Acetylcholine in cognitive impairment.

In this meta-analysis the researchers concluded that there was a critical threshold for the magnitude of the placebo response in antidepressant trials.

This paper on Clozapine monitoring extracted data from 16 studies to look at SE incidence rates.

D-cycloserine was associated with changes in activity in the Prefrontal Cortex seen at 1 week in the treatment of snake phobia in this fMRI study (n=20).

The baroreflex was investigated in this study and found to be reduced in Alzheimer’s Disease compared to people with mild cognitive impairment or healthy controls and associated with significant change after treatment.

Agitation in advanced Dementia was managed using a protocol (Treatment Routes for Exploring Agitation or TREA) in this study. The researchers assessed the efficacy of the protocol and found evidence of benefit.

The relationship between ACE inhibitor use and incidence of mild cognitive impairment was investigated in this study.

There was some preliminary evidence of the benefit of reduced peripheral vascular resistance and incidence of Dementia in this study.

There is a podcast on detection of Dementia here.

Neuroscience and Related Disciplines

Aspects of motivation are covered in this Scientific American article.

Professor Baron-Cohen and colleagues use functional MRI to look at embedded figures in this study.

Thought v arm-controlled cursors covered here.

Reasoning is improved in a foreign language according to this study.

Open Science

This is a neat time-lapse video showing how a research paper is written

There’s an interesting post here on digital publishing in research here which clarifies the relationship with open-access publishing.

There are #50 online tools for science teachers here.

There is an interesting article on citizen science here.

There is the fifth part in a series on Open-Access here.

Data transfer rates across networks are being pushed by the physics community.


The 40th Conference on Electrodiagnostic Medicine is taking place between February and March 2013.

Evolution/Evolutionary Psychiatry/Cultural Anthropology

An organism which ingests DNA from other simple organisms has been discovered.

Primates and resources allocation was examined one study examined in this video.

A paper looking at the evolution of vision 700 million years ago.

The atypical behaviour of herbivores is covered here.

The first settlements in Liverpool – 8000 years ago.


News Round-Up 2008-2011

Index: There are indices for the TAWOP site here and here Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

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