The Wellcome Trust have created this video on their YouTube channel illustrating the processes involved in transporting lipids around the body. The reason I have included this video here is that Apolipoprotein is a key molecule in lipid transport and Apolipoprotein E (and more specifically the E4 allele) is a risk factor for Alzheimer’s Disease. Furthermore APOE4 is described as a regulator of Alzheimer’s pathology upstream of both Tau and Amyloid in Small and Duff’s Dual Pathway Hypothesis.
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