Daily Archives: February 14, 2017

The Icelandic Mutation Protects Against Alzheimer’s Disease

DNA code analysis

The Icelandic population has been closely studied in terms of the population genetics. This has led to many important discoveries about diseases. One of these discoveries is the Icelandic mutation A673T. The Icelandic mutation is a variant of the Amyloid precursor protein gene. The Amyloid Cascade Hypothesis is a central hypothesis in the pathogenesis of Alzheimer’s Disease. This mutation has been associated with less Amyloid deposition and with more resilience to cognitive decline in people with cerebral pathology. There is a useful overview at the Alzforum.

Index: There are indices for the TAWOP site here and here

Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link.

TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link.

Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk.

Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

Conflicts of Interest: *For potential conflicts of interest please see the About section.

What’s a Kinkajou got to do with 21st Century Medical Terminology?

computer-keyboard-1380475577zzm

We looked at the use of Brodmann Areas in SNOMED CT® in this post. I noted that several Brodmann Areas were not included in the SNOMED CT® classification via the international browser. One of these Brodmann Areas is BA 51 which i’ve written about previously. This is also referred to as the Prepiriform Area. As SNOMED CT® has evolved from SNOP – the descriptive system for pathology and Brodmann’s undertook a histological analysis there is likely to be a robust reason for this omission.

The answer is likely to be the Kinkajou. The video below is produced by the Hotel Tinamu in Colombia.

The Kinkajou is nocturnal and is a member of the genus Potus from the Procyonidae family. Brodmann described Brodmann Area 51 not in humans but in the Kinkajou.

Appendix A – Other Posts in the Series on Health Information Exchanges

A Literature Review of 40 years of SNOMED

Arizona Statewide Health Information Exchange

A History of The Health Information Exchange in Pennsylvania

The Arkansas Health Information Exchange – SHARE

The California Health Information Exchange – Cal Index

Creating a Health Information Exchange in Arizona

Health Information Exchanges

Health Information Exchanges and Chronic Conditions

HIPPA and Health Information Exchanges

ICD-11 and SNOMED CT®

ICD-SNOMED-CT® Harmonisation

ICD-1 – Well…near enough

ICD-2

ICD-3

ICD-4

ICD-5

ICD-6

ICD-7

ICD-8

ICD-9

ICD-10

ICD-11

Körner Data and SNOMED: A Snapshot from 1988

Mapping ICD 9 (or 10) to SNOMED CT®

Over 1 Million Relationships: SNOMED CT ®

SNOMED CT® International Browser

Standardisation of Health Information Technology in New Zealand

Statisticians were Responsible for the Development of an International Classification of Diseases

Why Do We Need Electronic Record Systems to Talk to Each Other

Appendix B – Definition of Health Information Exchange

This is the definition of the Health Information Exchange that I use (Hersh et al, 2015)

Health information exchange (HIE), the electronic sharing of clinical information across the boundaries of health care organizations

Index: There are indices for the TAWOP site here and here

Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link.

TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link.

Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk.

Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

Conflicts of Interest: *For potential conflicts of interest please see the About section.