Daily Archives: April 4, 2017

The Brain Hypometabolism Hypothesis Part 33: GLUT 11

glucose_2

Professors Bernard Thorens and Mike Mueckler have written a review titled ‘Glucose Transporters in the 21st Century’. In terms of a Brain Hypometabolism Hypothesis, it is important to understand how Glucose is handled in the brain. Thorens and Mueckler reference 14 Glucose Transporters but not all of them are expressed in the brain.

Thorens and Mueckler note in their 2009 paper that not much is known about GLUT 11 other than an affinity for both Glucose and Fructose. A 2017 medline search using the search term “GLUT11” retrieved only 14 results and for “SLC2A11” also. Few of these papers post-dated the 2009 review and there was little discussion about the brain. This does not discount the possibility of a significant role in brain metabolism but it looks as though this is not an area of active research.

Appendix A – Citations

Thorens B, Mueckler M. Glucose transporters in the 21st Century. American Journal of Physiology – Endocrinology and Metabolism. 2010;298(2):E141-E145. doi:10.1152/ajpendo.00712.2009.

Index: There are indices for the TAWOP site here and here

Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link.

TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link.

Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk.

Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

Conflicts of Interest: *For potential conflicts of interest please see the About section

Standards Applicable to the Interoperability Framework

computer-keyboard-1380475577zzm

There is an NHS interoperability handbook here. Appendix A features a table which maps current standards to the interoperability framework layers. The standards that map onto the interoperability framework are

  • HL7v2 and v3
  • FHIR
  • Open EHR
  • IHE
  • ITK
  • ebXML
  • READ
  • SNOMED
  • NHS Number
  • ODS

General Posts to Date on Health Information Exchanges

Posts on Examples of Health Information Exchanges

SNOMED CT®/ICD Mapping and Harmonisation Posts

SNOMED CT® Posts

ICD 1-10 Posts

ICD-11 Posts

Index: There are indices for the TAWOP site here and here

Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link.

TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link.

Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk.

Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

Conflicts of Interest: *For potential conflicts of interest please see the About section