Professors Bernard Thorens and Mike Mueckler have written a review titled ‘Glucose Transporters in the 21st Century’. In terms of a Brain Hypometabolism Hypothesis, it is important to understand how Glucose is handled in the brain. Thorens and Mueckler reference 14 Glucose Transporters but not all of them are expressed in the brain.
In this paper it is noted that the GLUT family are divided into three classes.
Class I – GLUT1, GLUT2, GLUT3, GLUT4, GLUT14
Class II – GLUT5, GLUT7, GLUT9, GLUT11. Fructose is a subtrate for Class II GLUT’s.
Class III – GLUT6, GLUT8, GLUT10, GLUT12, GLUT13
This paper goes into some of the more subtle nuances of the GLUT’s.
Appendix A – Citations
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