In a paper by Sarnowski and colleagues, the researchers investigated subjects in the Framingham Heart study using data from whole genome analyses and MRI brain scans. They found evidence of several candidate genes for MRI phenotypes. These included
LRRTM4 – associated with Hippocampal Volume
ALCAM – White Matter Hyperintensities
UBL3 – Total Cerebral Brain Volume
There are seven other gene candidates with MRI phenotypes discussed in the paper.
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