The Brain Hypometabolism Hypothesis: Part 2


The ‘Brain Hypometabolism Hypothesis’ simply stated is that ‘Brain hypometabolism leads to neuropathology’. The hypothesis is more nuanced. In their 2016 paper, Cunnane and colleagues outline several supporting lines of evidence as the basis for their paper

(i) Lower glucose uptake in the frontal cortex of older adults

(ii) Regional deficits in brain glucose uptake in younger adults at risk of Alzheimer’s Type Dementia

(iii) Preservation of ketone uptake in the brain

(iv) Further evidence on consequences of ketone based interventions.

Index: There are indices for the TAWOP site here and here

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Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

Conflicts of Interest: *For potential conflicts of interest please see the About section.

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