Professors Bernard Thorens and Mike Mueckler have written a review titled ‘Glucose Transporters in the 21st Century‘. In their article they note that there are 14 Glucose transporters in humans and that many of their functions are not yet characterised. In terms of a Brain Hypometabolism Hypothesis, it is important to understand how Glucose is handled in the brain. Thorens and Mueckler reference 14 Glucose Transporters but not all of them are expressed in the brain.
In the paper they note that there is evidence that GLUT 2 plays a role in glucose ‘sensors’ in the central nervous system and the periphery.
There are a number of papers on GLUT2 and the brain including this one on a possible drug interaction with GLUT2 and this one on Ghrelin and the Hypothalamus.
Appendix A – Citations
Index: There are indices for the TAWOP site here and here
Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link.
TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link.
Responses: If you have any comments, you can leave them below or alternatively e-mail justinmarley17@yahoo.co.uk.
Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.
Conflicts of Interest: *For potential conflicts of interest please see the About section
The Amazing World of Psychiatry: A Psychiatry Blog 